Blar i forfatter "Lappegård, Jostein"

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    • Impact of Chronic Inflammation, Assessed by hs-CRP, on the Association between Red Cell Distribution Width and Arterial Cardiovascular Disease: The Tromsø Study 

      Lappegård, Jostein; Ellingsen, Trygve; Hindberg, Kristian; Mathiesen, Ellisiv B.; Njølstad, Inger; Wilsgaard, Tom; Løchen, Maja-Lisa; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-10)
      Red cell distribution width (RDW), a measure of variability in size of circulating erythrocytes, is associated with arterial cardiovascular disease (CVD), but the underlying mechanism remains unclear. We aimed to investigate the impact of chronic inflammation as measured by high sensitivity CRP (hs-CRP) on this relationship, and explore whether RDW could be a mediator in the causal pathway between ...

    • Impact of red cell distribution width on future risk of cancer and all-cause mortality among cancer patients – the Tromsø Study 

      Ellingsen, Trygve; Lappegård, Jostein; Skjelbakken, Tove; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10)

    • Plasma hepcidin is associated with future risk of venous thromboembolism 

      Ellingsen, Trygve; Lappegård, Jostein; Ueland, Thor; Aukrust, Pål; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018)
      Red cell distribution width (RDW) is associated with venous thromboembolism (VTE), but the underlying mechanism(s) is unclear. Iron deficiency is associated with high RDW, and studies suggest an association between iron deficiency and VTE. To assess whether iron deficiency is a risk factor for VTE that explains the association between RDW and VTE, we conducted a nested case-control study of 390 ...

    • Red Cell Distribution Width (RDW) and future risk of arterial cardiovascular diseases 

      Lappegård, Jostein (Doctoral thesis; Doktorgradsavhandling, 2018-05-28)
      Myocardial infarction (MI) and stroke rank as the top two killers on the world health organization’s causes of death statistics. Awareness of risk factors is important for targeted prevention of disease, and identification of novel risk factors can further improve the preventive measures. Red cell distribution width (RDW), a measure of the variability in size of the circulating erythrocytes, could ...

    • Red cell distribution width (RDW) and risk of arterial cardiovascular disease - a literature study 

      Lappegård, Jostein (Master thesis; Mastergradsoppgave, 2016-05-31)
      Myocardial infarction is the leading cause of death worldwide. Stroke is the third most common cause of death in the western world, and the primary cause of permanent disability. Both diseases are, in the majority of the cases, a result of atherosclerotic plaque formation and rupture. Many common risk factors and preventive options have already been discovered for these diseases, but the incidence ...

    • Red cell distribution width and carotid atherosclerosis progression: The Tromsø study 

      Lappegård, Jostein; Ellingsen, Trygve; Vik, Anders; Skjelbakken, Tove; Brox, Jan; Mathiesen, Ellisiv B.; Johnsen, Stein Harald; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-29)
      Red cell distribution width (RDW), a measure of the size variability of circulating erythrocytes, is associated with cardiovascular morbidity and mortality. We aimed to investigate whether RDW was associated with progression of atherosclerotic plaques in subjects recruited from the general population. Baseline characteristics, including RDW, were collected from 4677 participants in the fourth survey ...

    • Red Cell Distribution Width and Risk of Atrial Fibrillation and Subsequent Thromboembolism: The Tromsø Study 

      Hald, Erin Mathiesen; Løchen, Maja-Lisa; Lappegård, Jostein; Ellingsen, Trygve; Mathiesen, Ellisiv B.; Wilsgaard, Tom; Njølstad, Inger; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-28)
      <i>Introduction</i>- Red cell distribution width (RDW) is associated with cardiovascular diseases, including atrial fibrillation (AF) and venous thromboembolism (VTE). Whether RDW is a risk marker for thromboembolic events in AF patients is scarcely known. We aimed to assess the association between RDW and the risk of AF, and AF-related VTE and ischemic stroke, in a population-based cohort.<p> ...

    • Red cell distribution width is associated with future risk of incident stroke. The Tromsø study 

      Lappegård, Jostein; Ellingsen, Trygve; Skjelbakken, Tove; Mathiesen, Ellisiv B.; Njølstad, Inger; Wilsgaard, Tom; Brox, Jan; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-20)
      Red cell distribution width (RDW), a measure of the variability in size of the circulating erythrocytes, is associated with cardiovascular morbidity and mortality. We aimed to investigate whether RDW was associated with incident stroke and case fatality in subjects recruited from the general population. Baseline characteristics were obtained from 25,992 subjects participating in the fourth ...

    • Red Cell Distribution Width Is Associated With Incident Myocardial Infarction in a General Population: The Tromsø Study 

      Skjelbakken, Tove; Lappegård, Jostein; Ellingsen, Trygve; Barrett-Connor, Elizabeth; Brox, Jan; Løchen, Maja-Lisa; Njølstad, Inger; Wilsgaard, Tom; Mathiesen, Ellisiv B.; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Red cell distribution width is associated with incident venous thromboembolism (VTE) and case-fatality after VTE in a general population 

      Ellingsen, Trygve; Lappegård, Jostein; Skjelbakken, Tove; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)